Ibuprofen and testosterone

☑️@ibuprofen_and_testos · 4336 subscribers · Content 18+ 🔞
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Actual: In the clinical trial, ibuprofen caused no significant changes in the levels of testosterone or 17 -estradiol after 2 weeks or 44 days of ibuprofen administration. Ibuprofen exposure did lead to a change in ratio between testosterone (which stayed the same) and luteinising hormone, or LH (which went up).
4.4 rating 2025-04-24
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After 14 days, the men on ibuprofen had a reduced ratio of testosterone to luteinizing hormone, which stimulates testosterone production. This imbalance is

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by MB Maamar 2024 Cited by 79Ibuprofen suppressed testosterone and Leydig cell hormone m/z 156.1 → 114.1 for testosterone and ibuprofen, respectively. The

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In two weeks, the concentration of testosterone hormone dropped as ibuprofen concentrations grew in the blood of those taking ibuprofen

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Ibuprofen directly decreases testosterone levels, but the pituitary gland upregulates production (normalizing serum levels) by releasing more luteinizing hormone. Ibuprofen also suppresses testosterone through enzymes, including cytochrome P450, involved in steroid production.

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testosterone; Inh B, inhibin B; SHBG, sex hormone-binding protein; Total T, total testosterone. P ≤ 0.05, P ≤ 0.01. from publication: Ibuprofen alters

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The testosterone/luteinizing hormone ratio decreased in the ibuprofen study arm. This change is consistent with compensated hypogonadism.

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Ibuprofen lowered testosterone production in the tissues, but levels of the hormone remained the same in the men. This is because the pituitary

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