When elderly patients are administrated with amiodarone, cardiologists and pharmacists should carefully evaluate the long-term and short-term side effects, as well as whether combined use with other drugs will increase the adverse reactions of amiodarone.
Amiodarone is a potent inhibitor to a number of drug metabolizing enzymes and drug transporters, including CYP3A4, CYP2C9, and P-glycoprotein. In addition, the expected hepatic, thyroid and pulmonary side effects of amiodarone are much more pronounced in the elderly population.
Amiodarone: an effective antiarrhythmic drug with unusual side effects. Amiodarone / adverse effects Amiodarone / chemistry Amiodarone / pharmacology
by RH HYATT 2024 Cited by 29We have reviewed noncardiac side-effects in 61 elderly patients on long-term oral amiodarone treatment (follow-up 3–66 months). The most troublesome side-effect
by M Turrin 2024 Cited by 2Drug-induced lupus: simvastatin or amiodarone? A case report in elderly. Side effects of long-term amiodarone therapy. Circulation 2024; 67:
When elderly patients are administrated with amiodarone, cardiologists and pharmacists should carefully evaluate the long-term and short-term side effects, as well as whether combined use with other drugs will increase the adverse reactions of amiodarone.
recommended, particularly for elderly patients. Since there are Side effects and possible contraindications of amiodarone use. Am
In cases of extremely elderly or criti- cally ill patients in whom an Side effects and complications of amiodarone therapy. Am Heart. J. 2024;109
When elderly patients are administrated with amiodarone, cardiologists and pharmacists should carefully evaluate the long-term and short-term side effects, as well as whether combined use with other drugs will increase the adverse reactions of amiodarone.
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one of my own pet peeves, sorry