The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
The daily dose of morphine sulfate extended-release capsules must be limited to a maximum of 1600 Elimination of morphine is max min max min av max min. Page
There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max of 283nmol/L. The AUC of morphine is 225
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
Morphine (Oramorph) PRN, max hourly. You wish to prescribe One sixth of this is the 4hrly dose – prescribe 5mg Morphine subcutaneously PRN, max hourly.
The bioavailability of morphine is %. There is significant first-pass metabolism, therefore oral doses are 6 times larger than parenteral doses to achieve the same effect. Morphine reaches steady-state concentrations after hours. Parenteral morphine has a T max of 15 minutes and oral morphine has a T max of 90 minutes, with a C max
Morphine (Oramorph) PRN, max hourly. You wish to prescribe One sixth of this is the 4hrly dose – prescribe 5mg Morphine subcutaneously PRN, max hourly.
Regards, Jack