Alendronate vs prolia

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Actual: versus Prolia [1.4%, 12 out of 860]). Skin infections who had transitioned from previous alendronate therapy following 1-3 years treatment with Prolia.
4.8 rating 2025-04-23
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Three common medications that treat osteoporosis are Fosamax (alendronate), Boniva (ibandronate), and Prolia (denosumab).

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Prolia demonstrated superior fracture risk reduction vs alendronate, with a 36% to 50% greater reduction across multiple endpoints 1 Overall fracture relative risk reduction vs alendronate The overall fracture RRR for hospitalized vertebral fracture was 30% (95% CI, 0.40, 1.01), which was not statistically significant

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Comparing Alendronate vs Prolia ; Prescription only. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions.

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Anti-resorptive medications include the bisphosphonates (i.e. Actonel, Fosamax, alendronate, Boniva, Reclast), and denosumab (Prolia). These

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Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD 1 BMD data results are not meant to imply fracture efficacy and should not be extrapolated to predict differences in fracture efficacy.

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vs alendronate. Fiona, who is failing on her current bisphosphonate therapy Prolia compared to placebo. Most of these events were not specific to the

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The benefits of switching to Prolia vs staying on alendronate. In a 1-year study, women who switched from alendronate to Prolia showed a significant increase in bone mineral density (BMD) at the hip and the lumbar spine compared to women who stayed on alendronate, a commonly prescribed bisphosphonate (such as Fosamax ).

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Fosamax, or with both Prolia and Fosamax (when taken individually). Comparison of risk of osteoporotic fracture in denosumab vs alendronate treatment within 3

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Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD 1, increase in BMD vs alendronate The lower limit of the confidence interval excluded the prespecified noninferiority margin (-0.35% for total hip), thus showing the noninferiority of Prolia compared with alendronate

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