Three common medications that treat osteoporosis are Fosamax (alendronate), Boniva (ibandronate), and Prolia (denosumab).
Prolia demonstrated superior fracture risk reduction vs alendronate, with a 36% to 50% greater reduction across multiple endpoints 1 Overall fracture relative risk reduction vs alendronate The overall fracture RRR for hospitalized vertebral fracture was 30% (95% CI, 0.40, 1.01), which was not statistically significant
Comparing Alendronate vs Prolia ; Prescription only. Alendronate helps to reduce the risk of fracture in people with osteoporosis and some other bone conditions.
Anti-resorptive medications include the bisphosphonates (i.e. Actonel, Fosamax, alendronate, Boniva, Reclast), and denosumab (Prolia). These
Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD 1 BMD data results are not meant to imply fracture efficacy and should not be extrapolated to predict differences in fracture efficacy.
vs alendronate. Fiona, who is failing on her current bisphosphonate therapy Prolia compared to placebo. Most of these events were not specific to the
The benefits of switching to Prolia vs staying on alendronate. In a 1-year study, women who switched from alendronate to Prolia showed a significant increase in bone mineral density (BMD) at the hip and the lumbar spine compared to women who stayed on alendronate, a commonly prescribed bisphosphonate (such as Fosamax ).
Fosamax, or with both Prolia and Fosamax (when taken individually). Comparison of risk of osteoporotic fracture in denosumab vs alendronate treatment within 3
Prolia demonstrated noninferiority and superiority (vs alendronate) in total hip BMD 1, increase in BMD vs alendronate The lower limit of the confidence interval excluded the prespecified noninferiority margin (-0.35% for total hip), thus showing the noninferiority of Prolia compared with alendronate
then vs than
accept vs expect
alright vs all right
its vs it's
there vs their
waist vs waste
your vs you're, you are