Alkylating drugs

Common Characteristics of Alkylating Agents increased ability to repair DNA lesions decreased permeability to the alkylating drug.

Alkylating Agents. Alkylating agents are most active in the resting phase of the cell. These types of drugs are cell-cycle non-specific. There are several types of alkylating agents used in chemotherapy treatments:

Alkylating agents are reagents for effecting alkylation. Alkyl groups can also be removed in a process known as dealkylation. Alkylating agents are often

ALKYLATING AGENTS, PART 2/2: DRUG NAME: busulfan: procarbazine: CLASS: Other alkylating drugs: Other alkylating drugs: MECHANISM of ACTION: DNA damage in all phases of cell-cycle cancer cell death. Attach alkyl groups to DNA bases repair enzymes attempt to replace alkylated bases DNA fragmentation

Classes of chemotherapy drugs used for lymphoma include alkylating agents, plant alkaloids, anthracyclines, and proteasome inhibitors. Alkylating agents such as

Alkylating Agents Drugs Nitrogen mustards (for example, chlorambucil, bendamustine, ifosfamide, cyclophosphamide, melphalan, and mechlorethamine) Alkyl

Alkylating agents are a common class of chemotherapy drugs that work by transferring alkyl groups to DNA, causing cross-linkages and strand

Entry term(s): Alkylating Agents, Antineoplastic Alkylating Antineoplastic Agents Alkylating Antineoplastic Drugs Alkylating Antineoplastics

cancer drug therapy. I. ALKYLATING AGENTS AND PLATINUM COORDINATION COMPLEXES. HISTORY OF ALKYLATING ANTICANCER DRUGS. The discovery and initial