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The present invention is further related to a bioavailable extended release morphine dosage form for once-a-day oral administration. 30 mg morphine sulfate
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The present invention provides methods for the conversion of thebaine to a morphine derivative, such as hydrocodone. Novel ketal intermediates of the
Morphine was invented from opium as a potent medicine. It quickly became a standard painkiller used around the world. However, morphine use led to addiction.
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