Morphine activates a 'morphine ensemble'. The researchers Duloxetine may help elderly with depression Karolinska Institutet
Elderly. Because of the depressant effect on respiration, caution is necessary when giving morphine to the elderly. A reduction of dose is advisable. Page 3
Selected adverse drug reactions/Precautions unique to morphine: Active Elderly, cachectic, or debilitated patients: use with extreme caution due to
Elderly patients, in whom there is reduced If the patient has been using an analgesic other than morphine, estimate the morphine
Elderly. Because of the depressant effect on respiration, caution is necessary when giving morphine to the elderly. A reduction of dose is advisable. Page 3
Special populations: Reductions in dosage may be appropriate in the elderly If signs and symptoms suggestive of these skin reactions appear, morphine should
This formulation is not recommended for use in children under 12 years. In the Elderly. The dose of morphine should be reduced in elderly patients and
Morphine is substantially excreted by the kidney; risk of adverse reactions may be greater in patients with impaired renal function, and elderly patients are more likely to have decreased renal function. Hepatic Impairment. Morphine pharmacokinetics are significantly altered in patients with cirrhosis.
2 - Pharmacokinetics of morphine and oxycodone in frail elderly undergoing cardiac s . Intervention. Keyword : Frail, Morphine, Oxycodon
Regards, Jack