Acyclovir crystals

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Actual: The risk of deposition of acyclovir crystals in the kidney can be avoided by slow drug infusion over 1 to 2 h and volume repletion. Acyclovir-induced renal injury without acyclovir crystal obstruction is also described [21,22]. Another important side effect of acyclovir is neurological toxicity, mainly in patients with renal failure.
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A sulfadiazine crystal is shown on the left. Other medications that can cause urine crystals to form include indinavir, intravenous acyclovir

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Containing crystals Precipitation of crystals within the tubular lumen Acyclovir. Birefringent thin needles ? Isolated crystalluria. AKI. Page 92

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Acyclovir-induced renal failure is caused by precipitation of acyclovir crystals within the renal tubules, leading to obstructive nephropathy

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crystals in the renal tubules, is an occasional complication of Use of acyclovir, valacyclovir, and famciclovir in the first

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Acyclovir crystals do not have a unique morphology. However, long needle shaped crystals, with bright birefringence under polarized light microscopy that readily dissolve when diluted by water, saline, acid or base in the urine of patients receiving acyclovir IV is most likely to acyclovir crystalluria.

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Acyclovir crystals are needle-shaped, while those of indinavir may Acyclovir-induced renal failure. Clinical course and histology

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It is intended to provide eye drops comprising an acyclovir suspension whereby the precipitation/sedimentation and crystal transition of acyclovir can be

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by P Arriaga 2024Keywords: acute kidney failure, acyclovir nephrotoxicity, crystal nephropathy. crystals, but, without polarizing light microscopy, they can be missed.

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The diagnosis of acute crystal-induced kidney insufficiency by acyclovir was established by birefringent microscopy, which showed typical needle-shaped crystals

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