Amantadine withdrawal syndrome (AWS) is a rare but recognized cause of severe and persistent altered mental status sometimes with co-occurring extrapyramidal symptoms.
by KM Kampman 2024 Cited by 4Cocaine withdrawal symptom severity may predict response to medications that relieve cocaine withdrawal symptoms, such as amantadine. This paper describes a
We suggest that based on the available data, levodopa, dopamine agonists (DA), and amantadine should not be discontinued abruptly. Abrupt or sudden reduction of DA or amantadine in particular can lead to severe life-threatening withdrawal symptoms. Tapering off levodopa, COMT inhibitors, and MAO-B inhibitors may worsen motor and non-motor symptoms.
Amantadine (Symmetrel) Though not FDA-approved for ADHD, amantadine's dopamine-enhancing activity may also help improve ADHD symptoms. Research
Amantadine withdrawal, either after standard therapeutic use or in the days after an acute overdose, may result in hyperthermia and rigidity (similar to neuroleptic malignant syndrome). DIAGNOSIS Is based on a history of acute ingestion or is made by noting the aforementioned constellation of symptoms and signs in a patient taking amantadine.
Antiviral drugs amantadine and rimantadine for preventing and treating the symptoms of influenza A in adults. The drugs amantadine and rimantadine can both help prevent and relieve the symptoms of influenza A in adults, but amantadine has more adverse effects. The flu can be caused by many different viruses.
by KM Kampman 2024 Cited by 99Conclusions: Amantadine may be an effective treatment for cocaine-dependent patients with severe cocaine withdrawal symptoms. (Am J Psychiatry 2024; 152–
DOI: 10.1016/J.DRUGALCDEP.20 Corpus ID: ; A double-blind, placebo-controlled trial of amantadine, propranolol, and their combination for the treatment of cocaine dependence in patients with severe cocaine withdrawal symptoms.
by S Hughes 2024While our patient did not take Amantadine, the results Wellbutrin, Ropinerol, and iron supplementation, should ameliorate cocaine withdrawal symptoms.
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