Aminophylline Vesicant; alkaline agent (pH 8–10), Warming, Hyaluronidase ; Amiodarone Vesicant; acidic agent (pH 3.5–4.5), Warming, Hyaluronidase.
Amiodarone is an important drug in combating dangerous and potentially vesicant extravasation.1 The spectrum of harm, from mild to severe, includes
CYP3A4 and P-gp inhibitors (e.g. amiodarone, aprepitant, azole-antifungals Extravasation of a vesicant is a medical emergency. Monitor for signs of
Leaking of vesicant drugs into surrounding tissue Can cause severe local E.g. of drugs – Chemotherapeutic drugs, amiodarone, amphotericin
Vesicant. An agent capable of causing blistering, tissue sloughing, or necrosis when it escapes from the intended vascular pathway into surrounding tissue. Irritant. An agent capable of producing discomfort or pain along the internal lumen of the vein. Is amiodarone a vesicant? Amiodarone IV is a known vesicant. For infusions of longer than 1
alcohol, which may contribute to the drug's vesicant properties.9. Current recommendations for IV administration of amiodarone include
Infiltration is the accidental leakage of non-vesicant solutions out of the vein into the surrounding tissue. Amiodarone Arginine
similar to symptoms seen with infiltration of non-vesicants – Vesicant exposure, however, can progress to Acidic. - Amiodarone. -
amiodarone hcl oral tablet. 100 mg, 400 mg. 1 or 1b amiodarone hcl oral ITOTIC/VESICANT. AGENTS podofilox external gel. 2. QL podofilox external
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