Metabolism of rosuvastatin

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Actual: Metabolism: Rosuvastatin is not extensively metabolized; approximately 10% of a radiolabeled dose is recovered as metabolite. The major metabolite is N-
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One significant difference between atorvastatin and rosuvastatin is their metabolism pathway. Atorvastatin is metabolized extensively in the

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The metabolism of Rosuvastatin can be increased when combined with Acetaminophen. Acetazolamide, The metabolism of Rosuvastatin can be decreased when combined

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Rosuvastatin is primarily eliminated by excretion in the feces. The elimination half-life of rosuvastatin is approximately 19 hours. Metabolism. Rosuvastatin is not extensively metabolized; approximately 10% of a radiolabeled dose is recovered as metabolite.

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rosuvastatin metabolizes into the following: n-desmethyl rosuvastatin rosuvastatin acyl glucuronide rosuvastatin lactone. (source: PharmGKB). Molecular

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rosuvastatin - the principal isoenzyme involved in rosuvastatin metabolism is cytochrome P450 2C9. grapefruit juice. Fluvastatin is

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One significant difference between atorvastatin and rosuvastatin is their metabolism pathway. Atorvastatin is metabolized extensively in the

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Fluvastatin metabolized primarily by CYP2C9 and rosuvastatin minimally metabolized by the liver. Pitavastatin is metabolized via SLCO1B1, UGT1A3, UGT2B7.

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Lovastatin, simvastatin, and atorvastatin are all metabolized by CYP3A4, while statins such as fluvastatin and rosuvastatin are metabolized by

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One significant difference between atorvastatin and rosuvastatin is their metabolism pathway. Atorvastatin is metabolized extensively in the

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