Renin inhibitor drugs

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Actual: Renin-angiotensin-aldosterone system inhibitors are a group of drugs that act by inhibiting the renin-angiotensin-aldosterone system and include angiotensin-converting enzyme inhibitors (ACE inhibitors), angiotensin-receptor blockers, and direct renin inhibitors.
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renin inhibitors are latest among inhibitors of renin angiotensin aldosterone system Drug Chug96K views 5:07 Go to channel Angiotensin

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Drugs inhibiting the RAS include: renin inhibitors, ACE inhibitors and ARBs, which inhibit the enzymatic action of renin, the conversion of angiotensin I (Ang I) to Ang II and block the Ang II receptors, respectively. ACE inhibitors and ARBs block the RAS further downstream than renin inhibitors, which prevent the formation of renin.

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Renin inhibitors are antihypertensive drugs which block the first step in the renin-angiotensin system. Their mechanism of action differs from that of angiotensin converting enzyme inhibitors and angiotensin receptor antagonists, but like these drugs, renin inhibitors interrupt the negative feedback effects of angiotensin II on renin secretion.

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3,4 Hence, familiarity with drugs acting on the RAAS precedes the introduction of renin inhibitors. An effective oral renin inhibitor has not been marketed

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Direct renin inhibitors are a new class of drugs that act as non peptide renin inhibitors by binding competitively to renin and blocking the generation of angiotensin I from angiotensinogen. Direct renin inhibitors act on the juxtaglomerular cells of the kidney where the hormone is produced.

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Renin-angiotensin-aldosterone system (RAAS) inhibitors are a group of drugs that act by inhibiting the renin-angiotensin-aldosterone system

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Renin inhibitors or direct renin inhibitors are medications that affect the renin- angiotensin - aldosterone system and are used to treat high blood pressure.

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Direct renin inhibitors are a new class of drugs that act as non peptide renin inhibitors by binding competitively to renin and blocking the generation of angiotensin I from angiotensinogen. Direct renin inhibitors act on the juxtaglomerular cells of the kidney where the hormone is produced.

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Drugs acting on the RAAS include agents that inhibit renin synthesis and release; that is, the direct renin inhibitors and -adrenoceptor blockers, the ACE inhibitors, the ARBs, the aldosterone

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