Iveric Bio's Izervay is the second FDA-approved drug for geographic atrophy, after Apellis Pharmaceuticals' Syfovre.
Primary analysis at one year showed Izervay significantly reduced mean GA growth rates in treated patients vs. Izervay pegcetacoplan Syfovre
Izervay injections are given once per month, while Syfovre injections are given once every 25 60 days. If you have other questions about how Izervay and Syfovre compare, talk with your doctor.
IZERVAY vs sham. Masked image and adverse event analysis completed to SYFOVRE (pegcetacoplan injection) Prescribing Information. Waltham, MA
by MD Brown Jr 2024(Syfovre; Apellis Pharmaceuticals) and avacincaptad pegol intravitreal injection (Izervay; vs. placebo (p=0.07) in the primary endpoint
In 2024, the Food and Drug Administration (FDA) approved Izervay (avacincaptad pegol) and Syfovre (pegcetacoplan) to treat adults who have geographic atrophy caused by AMD. Izervay and Syfovre are the first-ever FDA-approved treatments for geographic atrophy and come as a solution that is injected directly into the eye and slows the progression
Syfovre and Izervay must not be used with other geographic atrophy drugs for commercial members, starting Nov. 24.
Note there is a factor of two favoring Astellas s chosen metric, given Izervay is monthly vs. Syfovre s majority use on the flexible EOM schedule, Citi said.
Syfovre (pegcetacoplan) or Izervay (avacincaptad pegol)? Vabysmo (faricimab) or Eylea (aflibercept)? Eylea in 2 milligrams (mg) or the new
then vs than
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