Morphine metabolism

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Actual: morphine, hydromorphone, oxymorphone undergo first pass metabolism. morphine gets metabolized to morphine-6-glucoronide, which is highly active
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effects of morphine morphine/codeine (opiates). ◦ Heroin metabolizes into codeine, codeine metabolizes into morphine. ◦ Relatively high false positive rate.

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Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4 Metabolism Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6

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Morphine is primarily metabolized into morphine-3-glucuronide (M3G) and morphine ^

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(codeine, morphine). Codeine metabolizes to morphine. Hydrocodone metabolizes to hydromorphone. All four drugs are controlled drugs. Morphine may also be

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by L DeDea 2024 Cited by 5codeine, and morphine). For prevention and treatment For example, codeine is metabolized to morphine and hydrocodone is metabolized to hydromorphone.

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Morphine is 35% protein bound, the metabolite morphine-3-glucuronide is 10% protein bound, and morphine-6-glucuronide is 15% protein bound. 4. Metabolism. Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. 4 Morphine can also be metabolized to codeine, normorphine, and morphine ethereal sulfate. 6

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Morphine is 90% metabolized by glucuronidation by UGT2B7 and sulfation at positions 3 and 6. Morphine can also be metabolized to codeine, normorphine, and

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(codeine, morphine). Codeine metabolizes to morphine. Hydrocodone metabolizes to hydromorphone. All four drugs are controlled drugs. Morphine may also be

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Codeine: Metabolizes to Hydrocodone and morphine Heroin: Metabolizes to 6-MAM and then to Morphine Morphine and Hydrocodone: metabolize to Hydromorphone.

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