Overall, lorazepam is fast-acting, but it has a long half-life. Lorazepam's half-life is about 12 hours, which means it decreases in
Temazepam may be a more appropriate choice for elderly patients due to its shorter half-life and lower risk of accumulation in the body. Lorazepam, on the other
For elderly and debilitated patients reduce the initial dose by lorazepam due to increased half-life and decreased total clearance.
Overall, lorazepam is fast-acting, but it has a long half-life. Lorazepam's half-life is about 12 hours, which means it decreases in
The elimination half-life is how long it takes for half of the drug to be For example, the equivalent dose of diazepam in an elderly individual on lorazepam
Pomara et al. [33] examined the effects of a single dose of lorazepam in elderly long-term users of lorazepam. half-life and a more frequent intake of
Ativan (lorazepam) is a short Hazardous benzodiazepine regimens in the elderly: Effects of half-life, dosage, and duration on risk of hip fracture.
In hepatic impairment / elderly - lorazepam 500 micrograms – 1 mg daily in divided In general compounds with higher potency and shorter half-life are
constipation, and confusion, especially in the elderly population. Probenecid, a medication used to treat gout, can increase the half-life of lorazepam by
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