alfaxalone for induction of anaesthesia in dogs anaesthetized for magnetic resonance imaging. Dogs' tracheas were extubated and the dogs
This formulation does not induce the release of histamine and it has been used successfully in dogs and cats. In cats, alfaxalone produces good
In dogs, the half-life (t ) of alfaxalone is approximately 25 minutes with the 2 mg/kg dose. Plasma clearance with a dose of 2 mg/kg is 59,4 12,9 mL/kg/min. In both cats and dogs, elimination of alfaxalone demonstrates a non-linear pharmacokinetics (dose-dependent) Alphaxalone metabolites are likely to be eliminated in the dog and cat.
by V Martín Bellido 2024 Cited by 7This clinical review summarises the pharmacological and anaesthetic properties of alfaxalone in the dog.
by J TAMURA 2024 Cited by 88IM alfaxalone produced a dose-dependent anesthetic effect with relatively mild cardiorespiratory depression in dogs.
In both dogs and cats the elimination of alfaxalone demonstrates non-linear (dose-dependent) pharmacokinetics. In vitro cat and dog hepatocyte studies show that
Alfaxalone produced good to excellent short-term anesthesia in unpremedicated dogs and Hypoventilation and apnea were the most prominent and dose-dependent
Alfaxan 10 mg/ml solution for injection for dogs, cats and pet rabbits alfaxalone. 2. STATEMENT OF ACTIVE AND OTHER SUBSTANCES alfaxalone 10 mg/ml. 3
Alfaxalone is a neuroactive steroid that is approved for use as an injectable anesthetic agent in dogs and cats. Alfaxalone can be used for sedation, induction of anesthesia, and for total intravenous anesthesia (TIVA).
Comments
Aside from upsetting me with potentially making dogs extremely sick though, I liked your story :)