Treatment for cml drugs
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These targeted therapies are now considered the standard treatment for CML; however, none of them cure CML, and so these drugs need to be taken indefinitely to
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Targeted therapy is the main treatment for almost all people with CML in the chronic phase. The targeted therapy drugs used to treat CML are called tyrosine kinase inhibitors (TKIs). Imatinib (Gleevec) is the standard TKI given when CML is first treated. The dose may be increased after 3 months if CML doesn't respond (is resistant) to treatment.
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How is CML treated? Targeted therapy drugs are the main treatment for chronic myeloid leukemia (CML), but some patients might also need other treatments.
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by PE Westerweel 2024 Cited by 62By sheer coincidence, another drug class used for the treatment of diabetes is under investigation for use as co-treatment in CML: the gliptins. PhCD34 CML
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In CML, TKIs target the abnormal BCR::ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. The first therapy given for a disease is called initial or first-line treatment. The following four TKI drugs are approved as first-line treatment for chronic phase CML:
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In CML, TKIs target the abnormal BCR-ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. Four TKI drugs are approved as initial therapy (first-line treatment) for chronic phase CML.
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What are the treatments for chronic myeloid leukemia (CML)? There are several different treatments for CML: Targeted therapy, which uses drugs or other substances that attack specific cancer cells with less harm to normal cells. For CML, the drugs are tyrosine kinase inhibitors (TKIs).
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In CML, TKIs target the abnormal BCR::ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. The first therapy given for a disease is called initial or first-line treatment. The following four TKI drugs are approved as first-line treatment for chronic phase CML:
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In CML, TKIs target the abnormal BCR::ABL1 protein that causes uncontrolled CML cell growth and block its function, causing the CML cells to die. The first therapy given for a disease is called initial or first-line treatment. The following four TKI drugs are approved as first-line treatment for chronic phase CML:
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