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Author: Admin | 2025-04-28
HomeBentylSide Effects Generic name: dicyclomineMedically reviewed by Drugs.com. Last updated on Jun 21, 2024.Note: This document provides detailed information about Bentyl.Applies to dicyclomine: oral capsules and tablets, oral solution, parenteral injection Side Effects associated with dicyclomine. Some dosage forms listed on this page may not apply specifically to the brand name Bentyl.Applies to dicyclomine: oral capsules and tablets, oral solution, parenteral injection.Side effects include:Most adverse effects are manifestations of pharmacologic effects at muscarinic-cholinergic receptors and usually are reversible when therapy is discontinued. Severity and frequency of adverse effects are dose related and individual intolerance varies greatly; although adverse effects occasionally may be obviated by a reduction in dosage, this also will likely eliminate potential therapeutic effects. If dosage of ≥80 mg daily cannnot be achieved because of intolerance, discontinue dicyclomine (the active ingredient contained in Bentyl) Dry mouth, dizziness, blurred vision, nausea, light-headedness (especially with the injectable form), drowsiness, weakness, nervousness. For healthcare professionalsApplies to dicyclomine: compounding powder, intramuscular solution, oral capsule, oral syrup, oral tablet.General adverse eventsThe most serious adverse reactions include cardiovascular and central nervous system symptoms.The most common adverse reactions are dizziness, dry mouth, vision blurred, nausea, somnolence, asthenia and nervousness, fever, tachycardia, agitation, and dry skin/mucous membranes.[Ref]GastrointestinalVery common (10% or more): Dry mouth (33%), nausea (14%)Rare (less than 0.1%): Constipation, anorexiaFrequency not reported: Thirst, delayed gastric emptying time, reduced gastric acid secretion, gastroesophageal refluxPostmarketing reports: Abdominal distension, abdominal pain, dyspepsia, constipation, dry mouth, nausea, vomiting[Ref]Nervous systemVery common (10% or more): Dizziness (40%)Common (1% to 10%): Somnolence, nervousnessRare (less than 0.1%): Sedation, headachePostmarketing reports: Dizziness, headache, somnolence, syncope[Ref]OcularVery common (10% or more): Blurred vision (27%)Frequency not reported: Follicular conjunctivitis, all muscarinic antagonists can precipitate glaucomaPostmarketing reports: Cycloplegia, mydriasis, blurred vision[Ref]OtherCommon (1% to 10%): AstheniaFrequency not reported: FatiguePostmarketing reports: Malaise, fatigue[Ref]DermatologicRare (less than 0.1%): RashPostmarketing reports: Allergic dermatitis, erythema, rash[Ref]RenalRare (less than 0.1%): Dysuria[Ref]GenitourinaryFrequency not reported: Urinary retention, impotence in male patientsPostmarketing reports: Suppressed lactation[Ref]CardiovascularPostmarketing reports: Palpitations, tachyarrhythmias, thrombosis, thrombophlebitis[Ref]HypersensitivityPostmarketing reports: Face edema, angioedema, anaphylactic shock[Ref]LocalPostmarketing reports: Local pain, edema, skin color change, reflex sympathetic dystrophy syndrome (caused by inadvertent IV injection)[Ref]PsychiatricPostmarketing reports: Delirium or symptoms of delirium such as amnesia (or transient global amnesia), nervousness, agitation, confusional state, delusion, disorientation, hallucination (including visual hallucination), and mania, mood (altered and pseudodementia).[Ref]RespiratoryPostmarketing reports: Dyspnea, nasal congestion[Ref]References1. Kagan G, Huddlestone L, Wolstencroft P (1984) "Comparison of dicyclomine with antacid and without antacid in dyspepsia." J Int Med Res, 12, p.
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