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Author: Admin | 2025-04-28
Vyvanse (lisdexamfetamine) and Adderall (amphetamine/dextroamphetamine) are two drugs approved by the U.S. Food and Drug Administration (FDA) for the treatment of attention-deficit/hyperactivity disorder (ADHD). Although both drugs are classified as central nervous system (CNS) stimulants, there are differences in how they are metabolized by the body and how effective they are in treating ADHD. This includes the immediate-release version of Adderall called Adderall IR and the extended-release version called Adderall XR. Vynanse can also be used to treat binge eating disorder (BED), while Adderall may be prescribed to treat narcolepsy (a type of sleeping disorder). This article explains the differences between Vyvanse and Adderall, including how they are used and which are more effective (and why). It also describes the recommended dosages, side effects, interactions, and when the drugs should not be used. Tom Werner / Getty Images Vyvanse vs. Adderall: Main Differences Vyvanse, Adderall IR, and Adderall XR are CNS stimulants that work by increasing levels of dopamine and norepinephrine in the brain. Dopamine and norepinephrine are chemical messengers called neurotransmitters that work by carrying messages from one nerve cell to the next. In people with ADHD, increased levels of dopamine and norepinephrine can help improve alertness, increase focus, and sustain thought, effort, and motivation. This doesn't mean that Vyvanse, Adderall IR, and Adderall XR are the same or can be used interchangeably. Metabolism and Absorption in the Body Vyvanse and Adderall differ in their active ingredients, but more importantly is how those ingredients are absorbed and metabolized by the body. Drug metabolization is the process wherein drugs are transformed by the body so that they can be eliminated more easily. This mostly occurs in the liver. Where Vyvanse differs is that it is a prodrug, whereas Adderall is an active drug. With an active drug like Adderall, the
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